In general the following technologies can be applied for CTS:
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Blending
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Fluidized bed granulation
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Wet granulation (tray or vacuum drying)
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Compaction
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Encapsulation (hard gelatine or HPMC capsules)
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Coating of particles and pellets
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Film-coating (rotating pan and fluidized bed)
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Pelletizing by extrusion and spheronization
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Melt extrusion
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Hot melt extrusion
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Nanomilling
Ranges from 250 g to 20 kg can be applied for most of the mentioned technologies.